Professor David Goldstein MBBS FRCP (UK) FRACP
Co-Lead Investigator, Australian Rare Cancer Portal
Professor Goldstein is a conjoint clinical professor. He has been involved in a variety of clinical research projects ranging from laboratory basic science to novel therapeutics trials to psychosocial aspects of Cancer care. He has been PI of a number of NHMRC and Cancer Australia funded therapeutic trials including both investigator initiated and as Australian PI for multinational studies. He has also been involved with psychosocial and cross cultural/CALD research for many years. His clinical interests are treatment of GI malignancies including pancreas cancer, colorectal cancer, anal carcinoma, hepatobilary and upper GI malignancy and renal cell carcinoma and lymphoma. He has been a Chief or Principal Investigator on $26,000,000 peer reviewed funded grants .
His activity over many years in one of the least common cancers and least studied, until recently, in the GI area – pancreas cancer, as well as GIST and biliary cancers gives him great insight into the challenges of approaching a suite of rare cancers. He has also been involved in several large scale epidemiologic studies, the most recent looking at pancreatic cancer. He has contributed to pivotal data resulting in PBS changes in approval for adjuvant gemcitabine in pancreas cancer, imatinib in metastatic and adjuvant GIST and first line nab-paclitaxel in pancreatic cancer.
Professor Goldstein is the Director of the UNSW Translational Cancer Research Network, a $6,000,000 CINSW funded program. He is the adult program leader of the UNSW National Cancer Survivors Centre and is involved with a research program associated with survivorship issues. As part of this activity, he is the Chief Investigator of a Cancer Institute NSW translational program grant of $3,100,000 to study the impact of chemotherapy induced peripheral neuropathy.
Professor Goldstein also actively participates in three laboratory research programs dealing with stromal biology, pancreas drug resistance and modeling optimal targeted therapies in sarcoma.
Professor Goldstein has been a member of the Australian Gastro-Intestinal Trials Group Scientific Advisory Committee for the last 12 years, was a board member and treasurer of the Gastro-Intestinal Cancer Institute for nine years, the longest serving president of the Clinical Oncology Society of Australia (COSA) and a member of both the American Society of Clinical Oncology (ASCO) and the American Association of Cancer Research. He serves on ASCO international committees engaged in supporting enhanced cancer service delivery in less developed countries.